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'Sugar switch' in the brain offers new path to treating depression | Removing the St3gal1 enzyme in healthy mice caused depressive symptoms, increasing St3gal1 in stressed mice had the opposite effect, easing those behaviors.
Chronic stress can rewire the brain, leading to a host of mental health issues. Now, scientists believe that one small sugar-adding process may act as a switch for depression, providing new insights into mood disorders – and a new target to treat them.
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