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The Microscopic Forces That Break Hearts


The Engineering Behind Organ Preservation

As part of ATP-Bio(a multi-institution research center tackling biological preservation), Rabin works to reveal the invisible forces that can silently fracture vitrified organs during cooling and warming. Rabin's models showed that optimizing nanoparticle concentration isn't just about getting enough particles, it's about achieving the right distribution pattern to counterbalance the natural stress profiles that develop during warming. What works perfectly at the rat scale might fail when applied to human organs, not because the principles are wrong, but because the physics of heat transfer and mechanical stress changes with size in counter-intuitive ways.

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