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6 Deaf Children Can Now Hear After a Single Injection


Several gene therapies aim to restore a protein necessary for transmitting sound signals from the ear to the brain.

Doctors carefully injected a tiny amount of liquid containing the viruses into a part of the children’s inner ears called the cochlea, a spiral-shaped chamber that contains hair cells. “The families are very, very excited,” says Yilai Shu, a head and neck surgeon at the Eye & ENT Hospital of Fudan University and an author on the paper. And in October, Regeneron’s Decibel Therapeutics in Boston reported improved auditory responses in one patient as part of an ongoing clinical trial.

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