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‘Set it and forget it’: automated lab uses AI and robotics to improve proteins
A self-driving lab system spent half a year engineering enzymes to work at higher temperatures.
A ‘self-driving’ laboratory comprising robotic equipment directed by a simple artificial intelligence (AI) model successfully reengineered enzymes without any input from humans — save for the occasional hardware fix. Conventional approaches tend to rely on developing an assay for a particular property — say, enzyme activity — and then screening vast numbers of mutated versions of the protein. So they turned to a cloud-based lab in California — an existing facility containing robotic equipment that can be directed remotely with computer code — and set their AI model to send instructions there.
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