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A 62-Year-Old German Man Got 217 Covid Shots—and Was Totally Fine
Hundreds of boosters over a 29-month period had little effect on the one person who tried it.
In cases of chronic exposure to a disease-causing germ, “there is an indication that certain types of immune cells, known as T-cells, then become fatigued, leading to them releasing fewer pro-inflammatory messenger substances,” according to co-lead study author Kilian Schober from the Institute of Microbiology – Clinical Microbiology, Immunology and Hygiene. The German man's extreme history of hypervaccination seemed like a good case to look for evidence of such tolerance and weaker responses. "In summary, our case report shows that SARS-CoV-2 hypervaccination did not lead to adverse events and increased the quantity of spike-specific antibodies and T cells without having a strong positive or negative effect on the intrinsic quality of adaptive immune responses," the authors concluded.
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