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A bioinspired capsule can pump drugs directly into the walls of the GI tract
Inspired by the jets of water squids use to propel themselves, an MIT-led team developed an ingestible capsule that releases drugs directly into the lining of the stomach or other organs of the digestive tract.
Graham Arrick SM ’20 and Novo Nordisk scientists Drago Sticker and Aghiad Ghazal are the lead authors of the paper, which appears today in Nature. The researchers came up with two ways to mimic this jetting action, using compressed carbon dioxide or tightly coiled springs to generate the force needed to propel liquid drugs out of the capsule. Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.
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