Get the latest tech news
A primer on the current state of longevity research
4k words, 19 minutes reading time
One of the strongest results here is an early 2023 study by Macip et al. demonstrating that cyclic expression of transcription factors in wild-type mice could extend their remaining lifespan by 109% when started at a very old age (124 weeks). There are some more easy-to-measure biomarkers on the table; grip strength, graying hair, and wrinkled skin all show strong correlation with age, even within mice and primates! There are papers that can draw strong connections between transcripts and protein expression levels to age-related cellular markers of age, organ dysfunction, and mortality risk.
Or read this on Hacker News