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A Startup Used AI to Make a Psychedelic Without the Trip


Mindstate Design Labs, backed by Silicon Valley power players, has created what its CEO calls “the least psychedelic psychedelic that’s psychoactive.”

While participants reported heightened emotions, associative thinking, enhanced imagination, and perceptual effects such as colors looking brighter, they did not experience hallucinations, self-disintegration, oceanic boundlessness and other typical features of a psychedelic trip. DiNardo envisions Mindstate’s drugs being administered similarly to the depression treatment Spravato, a form of ketamine—under the supervision of a health care provider who monitors the patient to ensure safety but isn’t guiding them through a talk therapy session, as in the case of Lykos. People who have taken psychedelics often report that the visions and altered state they experience during a trip allow greater emotional processing, helping them make sense of difficult or traumatic events that have happened to them.

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