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A Virus Found in Wastewater Beat Back a Woman’s ‘Zombie’ Bacteria
Viruses called phages are a promising treatment option for bacterial infections when antibiotics stop working, but they have limitations.
“We have found that a good place to look for phages is in environments where the bacteria you want to target are abundant,” says Daria Van Tyne, assistant professor of infectious diseases at Pitt and an author on a study about Cole’s case that was published today in the journal mBio. Van Tyne’s team mailed a sample of Cole’s bacteria to Duerkop’s lab, which had been studying phages that interact with E. faecium. Since the E. faecium was in Cole’s gut and bloodstream, the Pitt team made two formulations of phage: a drinkable version and an intravenous one given through a catheter.
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