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Aging Might Not Be Inevitable


There are biological underpinnings to aging—and so researchers are investigating cell manipulations, transfusions of young blood, and chemical compounds that can mimic low-calorie diets.

“If you’re a smaller species, there’s no point spending a lot of resources maintaining and repairing the body because the likelihood of being eaten or starved to death are high,” says Ramakrishnan. One of the most promising avenues of research involves the discovery of chemical compounds that can mimic the effects of a low-calorie diet, which is recognized as one of most well-established ways to slow down aging. This discovery came about when researchers first surgically connected the circulatory system of a young and old mouse—a technique called parabiosis—and observed that this procedure slowed down the symptoms of aging, lengthening the lifespan of the older animal by 10 percent.

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