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Alzheimer's could be treated by enhancing the brain's own immune cells | Researchers leveraging a technique called spatial transcriptomics, the method of examining tissue helped pinpoint the specific spatial location of gene activity inside a sample.
Researchers at Northwestern University have made a breakthrough in identifying a way for Alzheimer's disease to be treated far more effectively in the future – using the brain's own immune cells.
Researchers at Northwestern University have made a breakthrough in identifying a way for Alzheimer's disease to be treated far more effectively in the future – using the brain's own immune cells. The scientists at the Evanston, Illinois-based university leveraged a new-ish technique called spatial transcriptomics on human clinical-trial brains afflicted with Alzheimer’s disease. David Gate, an author of the paper that's appeared in Nature Medicine today, explained that this newly observed mechanism of the immune cells adapting their role in helping the brain recover could inform the development of treatments that "circumvent the whole drug process and just target these specific cells.” That might be a while away, as we don't yet have a way to target only those cells, but Gate notes that methods to do so are continually improving.
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