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An effective and rapidly degradable disinfectant from disinfection byproducts


Here, authors highlight ecological risks of a widely used disinfectant, chloroxylenol, and identify a more efficient and safer alternative from halo-phenolic disinfection byproducts, 2,6-dichlorobenzoquinone. They leverage seawater’s slightly alkaline nature to enhance its degradability via hydrolysis.

We first examined the antimicrobial activities of the selected DBPs and PCMX against Escherichia coli(gram-negative bacteria), which is the commonly used indicator of pathogenic contamination and has been identified as the driving agent for colorectal cancer 36. To verify the broad-spectrum antimicrobial potential of the DBPs, we examined their performance in inactivating Staphylococcus aureus(gram-positive bacteria), Candida albicans(fungi), and bacteriophage MS2 (viruses) at pH 7.2 and contact time 5 min. Safety and Effectiveness for Health Care Antiseptics; Topical Antimicrobial Drug Products for Over-the-Counter Human Use; Proposed Amendment of the Tentative Final Monograph; Reopening of Administrative Record.

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disinfectant