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Anti-aging "glue" naturally repairs damaged DNA to protect brain cells | A protein known as disulphide isomerase (PDI) assists against biological aging to ward off neurological degeneration including that seen in motor neuron, Alzheimer’s and Parkinson’s diseases.


A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor neuron, Alzheimer’s and Parkinson’s diseases.

A protein found in our cells has emerged as a secret weapon against biological aging, acting like a glue to repair damaged DNA and ward off neurological degeneration including that seen in motor neuron, Alzheimer’s and Parkinson’s diseases. “Just like a cut on your skin needs to heal, the DNA in our cells needs constant repair,” said neurobiologist Dr Sina Shadfar, from the university's Motor Neuron Disease Research Centre. The scientists found that PDI, on the other hand, has the power to cross into the nucleus of a cell and repair damage, which would essentially extend the life and function of these very important microscopic systems.

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