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Anti-aging molecule successfully restores multiple markers of youth
In pre-clinical trials, a small molecule effectively regrew neurons, reduced inflammation, and improved memory, speed, coordination, grip strength, and more. The finding could have a profound impact on aging and the diseases that accompany it.
They found one, and after administering this TERT-activating compound (TAC) to the rodents for six months, they witnessed the formation of new neurons in the memory centers of their brains known as the hippocampus, which helped the mice improve their performance on cognitive tests. “Epigenetic repression of TERT plays a major role in the cellular decline seen at the onset of aging by regulating genes involved in learning, memory, muscle performance and inflammation,” said study author Ronald DePinho. However, our deeper understanding of the molecular mechanisms driving the aging process has uncovered viable drug targets, allowing us to explore opportunities to intercept the causes of a variety of major age-related chronic diseases.”
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