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Antibodies Could Soon Help Slow the Aging Process
The protective proteins in our bodies aren’t just great for fending off infection—they could also fight the effects of getting older.
The first antibody approved for medical use was muromonab-CD3 in 1986, designed (ironically) to suppress the immune system and prevent organ rejection in transplant patients. In July 2024, scientists showed that antibodies targeting a protein called IL-11 could reduce inflammation in mice and extend their lifespans by 25 percent—up there with the best anti-aging drugs we know of, such as rapamycin. Greg Winter, who won the Nobel Prize for Chemistry in 2018 for work on isolating and mass-producing specific antibodies, told a conference in 2020: “I’m old now, and I have to take various blood pressure pills.
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