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Artificial intelligence helps predict whether antidepressants will work in patients


In patients with major depression disorder it is, thanks to use of artificial intelligence, now possible to predict within a week whether an antidepressant will work. By inputting a brain scan and an individual's clinical information into an AI algorithm, researchers from Amsterdam UMC and Radboudumc could see up to 8 weeks faster whether or not the medication would work. The results of this study are published today in the American Journal of Psychiatry.

By inputting a brain scan and an individual's clinical information into an AI algorithm, researchers from Amsterdam UMC and Radboudumc could see up to 8 weeks faster whether or not the medication would work. In a previous study conducted in the United States, MRI scans and clinical data were administered to 229 patients with major depression before and after a week of treatment with sertraline or placebo. "The algorithm suggested that those who had a lot of blood flow in the anterior cingulate cortex, the area of brain involved in emotion regulation, would be helped by the drug.

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