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Breakthrough drug successfully treats hard-to-control high blood pressure | The treatment, called baxdrostat demonstrates the ability to help patients whose blood pressure remains dangerously high despite standard therapy.
A new drug that significantly lowers "stubborn" blood pressure is on the horizon, following the results of its Phase III clinical trial. The treatment, called baxdrostat, has been hailed as the most promising advance in hypertension management in decades, demonstrating the ability to help patients…
The treatment, called baxdrostat, has been hailed as the most promising advance in hypertension management in decades, demonstrating the ability to help patients whose blood pressure remains dangerously high despite standard therapy. Excess aldosterone drives salt retention and raises blood pressure, but existing drugs that block its receptor, such as spironolactone (Aldactone), can cause hormonal side effects and dangerous rises in potassium. The results of the trial, which were presented at the European Society of Cardiology (ESC) Congress 2025 in Madrid this week, meant baxdrostat achieved all its benchmarks, giving AstraZeneca the green light to now seek FDA approval.
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