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Can ketones enhance cognitive function and protect brain networks?

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester have identified mechanisms in the brain’s hippocampal network that are rescued by ketones. These findings build on previous research showing that ketones can alleviate neurological and cognitive affects.

Researchers at the Del Monte Institute for Neuroscience at the University of Rochester have identified mechanisms in the brain’s hippocampal network that are rescued by ketones. Nathan A. Smith, MS, PhD ('13), associate professor of Neuroscience, and fellow researchers studied the mechanisms in the brain that break down when insulin resistance is suddenly present, like in trauma, but before symptoms manifest into chronic conditions, like diabetes or Alzheimer’s. “This research has implications for developing ketone-based therapies targeting specific neuronal dysfunctions in conditions involving insulin resistance/hypoglycemia like diabetes or Alzheimer's disease,” Smith said.

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