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Canine cancer drug fast-tracked for treating kids | Positive results from clinical trials of an immune therapy in dogs with bone cancer have been used to fast-track the development of the drug to treat children with the same cancer.
Positive results from clinical trials of an immune therapy in dogs with bone cancer have been used to fast-track the development of the drug to treat children with the same cancer. It highlights how leveraging our genetic similarity can benefit both species.
It’s called comparative oncology, and it’s the study of naturally occurring cancers in companion animals, such as dogs and cats, as models for the treatment of human disease. Tumor resection, including limb amputation, is the usual first-line treatment, while chemotherapy is given in combination with surgery to improve survival time by reducing the risk of metastasis. In January 2025, OST reported the results of its Phase 2b human clinical trials of OST-HER2 for osteosarcoma that had spread to the lungs and been completely surgically removed.
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