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Clever coating for medical devices stops clots by imitating a blood vessel
When a patient's blood flows through catheters, stents or other medical devices, there's always a risk that harmful clots may form. An experimental new bio-inspired coating could keep that from happening, without the use of blood-thinning drugs.
As a result, some scientists have developed anti-fouling coatings that repel the plasma proteins, keeping them from coming into contact with underlying synthetic surfaces. With this problem in mind, Kizhakkedathu and colleagues created a "selective protein interacting" (SPI) coating, which works like the natural inner lining of blood vessels. "By designing a coating that mimics the body’s natural approach to preventing clots, we’ve created a solution that could dramatically reduce the need for risky blood thinners before and after patients use these devices."
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