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Colossal BioSciences genetically engineers mouse with warm coat taken from woolly mammoth’s genes
Colossal Biosciences announced it has genetically engineered the Colossal Woolly Mouse, which has a warm coat like the woolly mammoth.
By successfully modifying seven genes simultaneously, Colossal’s team created mice with dramatically altered coat color, texture, and thickness reminiscent of the woolly mammoth’s core phenotypes. “By engineering multiple cold-tolerant traits from mammoth evolutionary pathways into a living model species, we’ve proven our ability to recreate complex genetic combinations that took nature millions of years to create. The Colossal scientists refined the list to include ten genes related to hair length, thickness, texture, and color as well as lipid metabolism that were compatible with expression in a mouse.
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