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Common amino acid found to speed up skin wound healing | New research reveals that a simple amino acid, serine, helps push stem cells to abandon hair growth in favor of wound healing, opening the door to new therapies for chronic wounds.


When the skin is injured, a stem cell’s survival instincts kick in. New research reveals that a simple amino acid, serine, helps push stem cells to abandon hair growth in favor of wound healing, opening the door to new therapies for chronic wounds.

The researchers found that in mice fed a diet low in serine and glycine, another amino acid, HFSCs delayed hair growth and accelerated wound repair, specifically the process of re-epithelialization or restoring the skin barrier. Similar ISR signatures were found in human skin models at the edge of healing wounds, suggesting the mechanism is evolutionarily conserved, meaning it has remained unchanged across different species over long periods. “No one likes to lose hair, but when it comes down to survival in stressful times, repairing the epidermis takes precedence,” said Elaine Fuchs, PhD, head of Rockefeller University’s Mammalian Cell and Biology and Development lab and the study’s corresponding author.

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