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Common daily pill slashes colorectal cancer’s return by 55% | A study involving more than 1,000 cancer patients has found that a low dose of aspirin halves the risk of colorectal tumors returning after surgery.
A study involving more than 1,000 cancer patients has found that a low dose of aspirin halves the risk of colorectal tumors returning after surgery. This readily available and inexpensive treatment could change health outcomes for a significant number of cancer survivors who have problematic gene…
The team then conducted a double-blind, randomized, placebo-controlled trial on this gene-altered cohort, with 626 patients receiving 160-mg aspirin daily for three years and the remainder taking a placebo. "Although we do not yet fully understand all the molecular links, the findings strongly support the biological rationale and suggest that the treatment may be particularly effective in genetically defined subgroups of patients," said Martling. "Aspirin led to a significantly lower incidence of colorectal cancer recurrence than placebo among patients with PIK3CA hotspot mutations in exon 9 or 20 and appeared to have a similar benefit among those with other somatic alterations in PI3K pathway genes."
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