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Common diabetes drug significantly improves osteoarthritic knee pain | Effective pain reduction and improved mobility may mean that people with the condition can delay invasive knee replacement surgery.


A mainstay diabetes medication reduced pain and stiffness and improved function in overweight people with knee osteoarthritis, a new study has found. Effective pain reduction and improved mobility may mean that people with the condition can delay invasive knee replacement surgery.

A mainstay diabetes medication reduced pain and stiffness and improved function in overweight people with knee osteoarthritis, a new study has found. In addition to pain-relieving medications like non-steroidal anti-inflammatory drugs(NSAIDs), non-surgical treatments include exercise, weight management, physical therapy, and steroid injections into the joint. The researchers said that the findings suggest that metformin could be used “off-label,” that is, in a way not specifically approved in its product information, as part of the OA treatment pathway, after discussions between a patient and their treating doctor.

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