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Could Down syndrome be eliminated? Japanese scientists use CRISPR to target extra chromosome
A groundbreaking study from Japan has introduced the possibility of eliminating the genetic cause of Down syndrome through cutting-edge gene-editing technology, reports a Kazinform News Agency correspondent.
Using CRISPR-Cas9, researchers at Mie University have successfully removed the extra copy of chromosome 21 from affected cells in laboratory settings — a scientific milestone that could reshape future approaches to treating the condition. This additional genetic material disrupts normal cellular processes, leading to a range of developmental and health issues, including intellectual disabilities, congenital heart defects, and increased risk for Alzheimer’s disease. “When we start listening to what people with Down syndrome themselves have to say about this … they find it disturbing … and we hear the same stories from their families,” told ABC News Australia Astridur Stefansdottir, a medical doctor and professor in applied ethics at the University of Iceland.
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