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CRISPR could disable and cure HIV, suggests promising lab experiment | The gene-editing technique CRISPR disabled HIV that lay dormant in immune cells in a lab experiment, raising hopes for an eventual cure
The gene-editing strategy could be a way to disable HIV that lies dormant in immune cells, meaning people would no longer need to take daily medication
“These findings represent a pivotal advancement towards designing a cure strategy,” researcher Elena Herrera Carrillo at the University of Amsterdam in the Netherlands said in a statement. By changing the DNA sequence being targeted, the system can potentially be turned into a form of gene therapy for many conditions, with the first such treatment having been approved last year in the US and UK as a cure for sickle cell anaemia. Jonathan Stoye at the Francis Crick Institute in London says that although the results are encouraging, the next step is trials in animals and eventually people to show the treatment can reach all the immune cells with dormant HIV.
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