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DeepMind adds a diffusion engine to latest protein-folding software
Major under-the-hood changes let AlphaFold handle protein-DNA complexes and more.
And all of that depends on the ability of the protein's string of amino acids to fold up into a complicated yet specific three-dimensional shape that enables it to function. Up until this decade, understanding that 3D shape meant purifying the protein and subjecting it to a time- and labor-intensive process to determine its structure. But that changed with the work of DeepMind, one of Google's AI divisions, which released Alpha Fold in 2021, and a similar academic effort shortly afterward.
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