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Defeating AIDS: MIT reveals new vaccination method that could kill HIV in just two shots | MIT researchers found that the first dose primes the immune system, helping it generate a strong response to the second dose a week later.
MIT researchers have developed a new HIV vaccination method that generates a strong immune response with just two doses, one week apart.
Several years ago, MIT researchers showed that administering a series of escalating doses of an HIV vaccine over two weeks could help overcome a part of that challenge by generating larger quantities of neutralizing antibodies. Irvine’s lab developed the nanoparticle, which acts as an adjuvant to help recruit a stronger B cell response to the vaccine. In the new study, the MIT team investigated how this response develops and explored whether they could achieve the same effect using fewer vaccine doses.
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