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Depression, schizophrenia and bipolar disorder linked with ancient viral DNA
‘Hervs’ date back hundreds of thousands of years – and play an important role in regulating genes.
These RNA molecules can then serve as intermediaries leading to the production of specific proteins, or help to regulate other parts of the genome. These molecules have the potential to exert a wide range of functions, as they can travel across cellular compartments to execute different roles. By linking Herv expression in the brain with psychiatric disorders, our research recognises the importance of these mysterious sequences in the human genome, which have been ignored for years.
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