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Drug delivery gets a precision upgrade with ultrasound tech | Ultrasound-sensitive nanoparticles release drugs primarily at their intended targets in the body
How do you send drugs to specific parts of the body so they do their job and avoid causing side effects elsewhere? According to researchers at Stanford University, the answer is a combination of nanoparticles, a pulse of ultrasound, and sugar.
The researchers also tested the targeted delivery of ketamine to the rats' prefrontal cortex – which regulates emotional stress – to successfully calm their anxious behavior. Professor Airan had looked into ultrasound tech for drug delivery too, and had devised a system in 2018 that was less-than-perfect because the drug-laden nanoparticles he was working with weren't stable at body temperature, and would allow the medication to seep out all over the place. That means that it will be a few years before it receives the necessary approvals for commercialization, but it certainly seems like a promising approach to enabling the use of psychotropic drugs to treat mental health issues while limiting potential side effects.
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