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DSM Disorders Disappear in Statistical Clustering of Psychiatric Symptoms (2024)
Whither Major Depression?
The final high order structure included 8 spectra: Externalizing, Harmful Substance Use, Mania/Low Detachment, Thought Disorder, Somatoform, Eating Pathology, Internalizing, and Neurodevelopmental and Cognitive Difficulties. Due to the symptom heterogeneity of DSM constructs, they are either broken down into smaller homogenous syndromes or they merge into higher-order clusters such as subfactors and spectra. If Forbes et al. are correct, the thing itself isn’t a fixed, stable entity but consists of variable and heterogenous subsets of internalizing and neurocognitive symptoms.
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