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Exercise rewires the brain, helping mice forget traumatic and addictive memories


Increased neuron growth in the hippocampus through exercise or genetic approaches helps mice forget strong, maladaptive memories, raising the promise of new PTSD or drug addiction treatments.

The hippocampus, a brain region important for forming memories linked to specific places and contexts, produces new neurons daily in an area called the dentate gyrus. Risako Fujikawa, Adam I. Ramsaran, Axel Guskjolen, Juan de la Parra, Yi Zou, Andrew J. Mocle, Sheena A. Josselyn & Paul W. Frankland, Molecular Psychiatry(2024). Increased neuron growth in the hippocampus through exercise or genetic approaches helps mice forget strong, maladaptive memories, raising the promise of new PTSD or drug addiction treatments.

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