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Finally: A diagnostic test for chronic fatigue syndrome?


While it's estimated that millions worldwide suffer from chronic fatigue syndrome, a test for the condition still doesn't exist. That could be set to change with the release of a new study that finds the condition's fingerprint in the gut microbiome.

New research from the Jackson Lab, however, has found a unique biological fingerprint of the disease in the gut microbiome, which should not only give ME/CFS patients hope that their symptoms will be taken seriously, but also open the door to new treatment options. “Despite diverse data collection methods, common disease signatures emerged in fatty acids, immune markers, and metabolites,” said lead researcher Julia Oh. “MAIT cells bridge gut health to broader immune functions, and their disruption alongside butyrate and tryptophan pathways, normally anti-inflammatory, suggests a profound imbalance,” said study co-author Derya Unutmaz.

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