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First-ever human skin atlas provides ‘molecular recipe’ to build skin, heal scars | Through this organoid, the researchers were able to study how immune cells, specifically macrophages, contribute to blood vessel formation.
This research could lead to advancements in regenerative medicine, especially for those requiring skin grafts or hair restoration treatments.
These methods allowed scientists to examine the molecular dynamics of human skin at the individual cell level, providing invaluable insights into the genetic and cellular processes involved. Dr Hudaa Gopee, co-first author from Newcastle University, said in the press release, “We’re excited to have made a skin organoid model that grows hair. In this process, we uncovered a new, important role of immune cells in promoting the growth of blood vessels in developing skin tissue, which could help improve other organoid models.
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