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Frozen human brain tissue can now be revived without damage | Using a new approach, scientists have successfully frozen and thawed brain organoids and cubes of brain tissue from someone with epilepsy, which could enable better research into neurological conditions
Using a new approach, scientists have successfully frozen and thawed brain organoids and cubes of brain tissue from someone with epilepsy, which could enable better research into neurological conditions
A new technique has allowed scientists to freeze human brain tissue so that it regains normal function after thawing, potentially opening the door to improved ways of studying neurological conditions. The researchers then placed these organoids — which measured 4 millimetres across on average — in different chemical compounds, such as sugars and antifreeze, that they suspected might help keep the brain cells alive while frozen and able to grow after being thawed. The combination that led to the least cell death and most growth was a blend of chemical compounds called methylcellulose, ethylene glycol, DMSO and Y27632 — which the scientists named “MEDY”.
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