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Gluing proteins together kills cancer super selectively | Scientists have demonstrated a creative new way to kill cancer cells effectively, with few side effects. Gluing two particular proteins together tricks the tumors into destroying themselves.
Scientists have demonstrated a creative new way to kill cancer cells effectively, with few side effects. Gluing two particular proteins together tricks the tumors into destroying themselves.
Understandably, oncogenes and the proteins they encode are a common target for cancer treatments, but the new study, from researchers at Stanford, tackles the problem from a different angle. Mutated BCL6 will sit on DNA right near specific genes that promote apoptosis, keeping them switched off so the cancer cells can continue to grow and divide unchecked. The team is currently testing the compound in mice with diffuse large cell B-cell lymphoma, with hopes that the general idea could eventually be applied to treat a wide range of cancers with extreme selectivity.
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