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Handheld diagnostic that can isolate biomarkers for different diseases using sound waves, from a single drop of blood, in around an hour.


Nobody enjoys giving blood samples, but it’s a necessary part of many hospital stays and doctor visits. Soon we might not have to, thanks to a new device that can isolate biomarkers for different diseases using sound waves, from a single drop of blood, in around an hour.

Usually, blood tests involve taking a sample with the dreaded needle in the arm, which is then sent off to a lab to check for certain molecules that can indicate the presence or progression of a disease or condition. These cell-sized particles are designed to respond to pressure from sound waves, and can be coated with different materials so that they capture a specific biomarker, like viruses or proteins. “In our paper, we demonstrate that this pipette and particle system can offer the same sensitivity and specificity as a gold-standard clinical test can but within an instrument that radically simplifies workflows,” said Wyatt Shields, senior author of the study.

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