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Himalayan fungus compound tweaked for 40x anti-cancer boost
By using a compound derived from a Himalayan fungus and used for centuries in Chinese medicine as a jumping off point, scientists have developed a new chemotherapy drug with powerful anti-cancer effects. Doing so involved chemically altering the compound to better infiltrate cancerous cells, which…
By using a compound derived from a Himalayan fungus and used for centuries in Chinese medicine as a jumping off point, scientists have developed a new chemotherapy drug with powerful anti-cancer effects. It works by attaching small chemical groups to the compound that make it more resistant to breakdown in the bloodstream, and also enables them to enter cancer cells without the help of nucleoside transporters. The compound was combined with a checkpoint inhibitor called pembrolizumab for this part of the NuTide:701 study, and NuCana presented final data at the ESMO Congress in Barcelona last year.
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