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I got dysentery in a human challenge trial
On turning 30 in a human challenge trial ward.
It consisted of some spaces for nurses and testing, about 6 bedrooms of various sizes (each with their own half-bath), two separate areas with two shower stalls each, a “kitchen” with snacks and where the meals were delivered to, a closet with washer and dryer, and a rec room with couches and a TV and a pool and foosball table. The influx of PMN cells across the epithelial layer in response to Shigella disrupts the integrity of the epithelium allowing lumenal bacteria to cross into the sub-mucosa in an M-cell independent mechanism. But in this case, shigatoxin-producing Shigella and other pathogenic Escherichia coli have different enough clinical presentations that the distinction is still medically valuable, so accurate nomenclature has bowed its head to practicality.
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