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Immune system found to trigger fear, but psychedelics block it | The finding could improve the treatment of both mental, emotional and physical afflictions.


A new study has uncovered a previously unknown link between the immune system and the fear response, and how psychedelics can play a role in suppressing it. The finding could improve the treatment of both mental, emotional and physical afflictions.

A new study has uncovered a previously unknown link between the immune system and the fear response, and how psychedelics can play a role in suppressing it. Diving deeper into the role psychedelics have on our bodies, researchers at Mass General Brigham found that during chronic stress, our immune systems send inflammatory cells called monocytes to the amygdala, the brain region responsible for processing our emotions – especially fear, anxiety and aggression. Most interestingly, though, using mouse models, the team found that the psychedelics psilocybin and MDMA blocked the monocytes from collecting in the brain, thus hampering the immune system's ability to spark fear and create an inflammatory response.

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