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Implantable device detects opioid overdose and automatically administers naloxone in animal trials


Implantable device detects opioid overdose and automatically administers naloxone in animal trials Researchers have developed an implantable device that can detect an opioid overdose and automatically administer the life-saving drug naloxone. The device, which the researchers call

The device, which the researchers call “iSOS,” includes multiple sensors that allow it to continuously monitor the user’s heart and respiratory systems and a pump that rapidly administers naloxone when needed. “Having an automated robotic system that is able to sense and reverse opiate overdose could be transformational, particularly for high-risk populations,” says senior author Giovanni Traverso (@cgtraverso), a clinician and biomedical engineer at MIT, Brigham and Women’s Hospital, and the Broad Institute. “Our proposed solution tackles these unmet needs by developing a miniaturized robotic implant equipped with multi-sensing modalities, continuous monitoring capabilities, on-board decision-making, and an innovative micro-pumping mechanism.”

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