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Japan’s green light for making human embryos from stem cells takes us into uncharted territory using CRISPR, IPSCs, and IVF, potentially changing our entire species


“We need to be talking much more about the whole constellation of possibilities around human stem cell IVF,” writes Paul Knoepfler.

Sandy Huffaker/Getty Images/STAT Knoepfler is STAT’s Lab Dish columnist and professor of cell biology and human anatomy at UC Davis School of Medicine. Scientists in Japan and around the world are quickly working toward making viable human eggs and sperm from stem cells, a process called in vitro gametogenesis, or IVG. Those stem cell-derived sperm and eggs could be used for vitro fertilization (IVF) to generate human embryos for research or, one day, making babies.

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