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Ketamine for Depression: How It Works (2024) [video]


In this video, Yale Medicine psychiatric specialists discuss how ketamine can help treat depression.

Ketamine seems to allow for a regrowth of synapses (connections between neurons), explains John Krystal, MD, chair of the Yale School of Medicine Department of Psychiatry. There's evidence that ketamine can have a very rapid onset of effects in neuroplasticity, says Gerard Sanacora, MD, PhD, director of the Yale Depression Research Center. In the video above, Yale experts talk more about ketamine and how it can work with a comprehensive treatment plan that includes psychotherapy, such as cognitive behavioral therapy (CBT).

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