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Lab-grown mini-brain given epilepsy drug learns in real time | For the first time, a lab-grown brain-computer system has demonstrated that human neurons living and evolving in an artificial system respond to medication by learning, in real time, in a game-like environment.


For the first time, a lab-grown brain-computer system has demonstrated that human neurons living and evolving in an artificial system respond to medication by learning, in real time, in a game-like environment. Subjected to anti-seizure drugs, Cortical Labs' disease-modeled neurons didn't just show…

As extensively covered in our visit to the company's Melbourne laboratory, the CL1 biological computer features lab-grown neurons from human stem cells on a silicon base in a life-supporting specially designed box. "The ability to observe how living neurons react to real-time stimulation and drug treatment opens up entirely new ways to develop, test, and personalize therapies – all without relying on animal models. While the SBI system is obviously a much simpler model than the human brain, and the drug intervention focused just on glutamatergic neurons, it's nonetheless a big milestone for Cortical Labs, which has invested years of work to get to this point.

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