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Lactate helps cancer cells resist chemotherapy


Addition of a lactyl group to a specific amino-acid residue promotes the repair of DNA damage in tumour cells.

Metabolomics analysis reveals that lactate in tumour cells promotes resistance to chemotherapy, and sheds light on the molecular mechanism that underlies this unexpected role of lactate in cancer. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

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