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Landmark study reveals cell-level brain changes tied to PTSD | The findings paint a detailed picture of how trauma leaves lasting marks on the brain—right down to the cell level.
Post-traumatic Stress Disorder (PTSD) isn’t caused by just one faulty switch in the brain; it’s more like a tangled orchestra of genes and cells thrown off-key by trauma. With many genetic players involved, scientists are still piecing together the full score.
Post-traumatic Stress Disorder (PTSD) isn’t caused by just one faulty switch in the brain; it’s more like a tangled orchestra of genes and cells thrown off-key by trauma. In the new study, published in Nature, researchers analyzed over two million cell nuclei from the brain tissue of 111 people, focusing on a region called the dorsolateral prefrontal cortex, which is linked to decision-making and emotional control. They reveal how specific cell types in the prefrontal cortex respond to stress at a molecular level, helping scientists understand how PTSD can reshape the brain’s function over time.
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