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Low Dose of Lithium Reverses Alzheimer's Symptoms In Mice
An anonymous reader quotes a report from New Scientist: People withAlzheimer's disease have lower levels of lithium in their brains, and giving lithium to mice with symptoms of the condition reverses cognitive decline. Together, the findings suggest that lithium deficiency could be a driver of Alzhe...
[...] [Bruce Yanknerat Harvard University] and his colleagues analyzed levels of 27 metals in the brains of 285 people after they died, 94 of whom were diagnosed with Alzheimer's disease and 58 of whom had mild cognitive impairment, a precursor of the condition. Lithium levels in the prefrontal cortex -- a brain region crucial for memory and decision-making -- were about 36 percent lower, on average, in people with Alzheimer's disease than in those without any cognitive decline. In those with Alzheimer's disease, clumps of proteins called amyloid plaques contained nearly three times the amount of lithium as plaque-free regions of their brain.
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