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Malaria vaccine delivered by a mosquito bite
Bites from insects infected with modified malaria parasites boosted immunity and stopped people from contracting the disease.
“These findings represent a significant step forward in malaria vaccine development,” says Julius Hafalla, an immunologist at the London School of Hygiene & Tropical Medicine. The study, which was published 1 in The New England Journal of Medicine on 20 November, exposed participants to bites from mosquitoes that had a modified version of the Plasmodium falciparum parasite, which causes malaria. The research team had previously trialled the effectiveness of a modified malaria parasite, called GA1, that is designed to stop developing about 24 hours after infection in humans 2.
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