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Moment of heart's formation captured in images for first time
Time-lapse footage reveals cardiac cells in a mouse embryo begin to organise themselves during early development
“This is the first time we’ve been able to watch heart cells this closely, for this long, during mammalian development,” said the study’s senior author, Dr Kenzo Ivanovitch of University College London’s Great Ormond Street Institute of Child Health. The researchers found that early during gastrulation (about six days into mouse embryo development), cells contributing solely to the heart emerged rapidly and behaved in highly organised ways. “This fundamentally changes our understanding of cardiac development by showing that what appears to be chaotic cell migration is actually governed by hidden patterns that ensure proper heart formation.”
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