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Nano-cubosome eyedrops that can ferry protective compounds all the way to the retina, target macular degeneration without needles


Scientists have developed a new eyedrop that can ferry protective compounds all the way to the retina, paving the way for a less-invasive injection-free method of managing sight-stealing diseases such as age-related macular degeneration (AMD).

The team developed a patented nanotech “cubosome” delivery system – like tiny lipid boxes that shield fragile cargo – then loaded it with lutein extracted from Gac fruit. “Our cubosome carriers act like tiny shields, keeping the compound safe and releasing it in a controlled way once it’s inside the eye,” said co-lead researcher Charlotte Conn, from RMIT’s School of Science. Plant-derived compounds (not just carotenoids like lutein and zeaxanthin but also polyphenols) that act on inflammatory and oxidative pathways have the potential to help preserve eye health and protect against age-related degeneration.

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